Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/joomla/import.php on line 29

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/joomla/import.php on line 32

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JRequest::clean() should not be called statically in /home/zephyr/public_html/libraries/joomla/import.php on line 33

Strict Standards: Non-static method JRequest::_cleanArray() should not be called statically in /home/zephyr/public_html/libraries/joomla/environment/request.php on line 463

Strict Standards: Non-static method JRequest::_cleanArray() should not be called statically in /home/zephyr/public_html/libraries/joomla/environment/request.php on line 464

Strict Standards: Non-static method JRequest::_cleanArray() should not be called statically in /home/zephyr/public_html/libraries/joomla/environment/request.php on line 465

Strict Standards: Non-static method JRequest::_cleanArray() should not be called statically in /home/zephyr/public_html/libraries/joomla/environment/request.php on line 466

Strict Standards: Non-static method JRequest::_cleanArray() should not be called statically in /home/zephyr/public_html/libraries/joomla/environment/request.php on line 467

Strict Standards: Non-static method JRequest::_cleanArray() should not be called statically in /home/zephyr/public_html/libraries/joomla/environment/request.php on line 468

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/joomla/import.php on line 35

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/joomla/import.php on line 38

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/joomla/import.php on line 39

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/joomla/import.php on line 46

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/joomla/import.php on line 47

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/joomla/import.php on line 50

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/joomla/import.php on line 53

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/joomla/import.php on line 54

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/joomla/import.php on line 57

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/joomla/import.php on line 58

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JFactory::getApplication() should not be called statically in /home/zephyr/public_html/index.php on line 31

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Redefining already defined constructor for class JObject in /home/zephyr/public_html/libraries/joomla/base/object.php on line 57

Strict Standards: Non-static method JApplication::getInstance() should not be called statically in /home/zephyr/public_html/libraries/joomla/factory.php on line 46

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JApplicationHelper::getClientInfo() should not be called statically in /home/zephyr/public_html/libraries/joomla/application/application.php on line 132

Strict Standards: Declaration of JSite::getRouter() should be compatible with & JApplication::getRouter($name = NULL, $options = Array) in /home/zephyr/public_html/includes/application.php on line 377

Strict Standards: Declaration of JSite::getPathWay() should be compatible with & JApplication::getPathway($name = NULL, $options = Array) in /home/zephyr/public_html/includes/application.php on line 377

Strict Standards: Declaration of JSite::getMenu() should be compatible with & JApplication::getMenu($name = NULL, $options = Array) in /home/zephyr/public_html/includes/application.php on line 377

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/joomla/registry/registry.php on line 19

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Declaration of JSession::set() should be compatible with JObject::set($property, $value = NULL) in /home/zephyr/public_html/libraries/joomla/session/session.php on line 725

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/joomla/session/session.php on line 19

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/joomla/html/parameter.php on line 21

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Declaration of JRegistryFormatINI::objectToString() should be compatible with JRegistryFormat::objectToString(&$object) in /home/zephyr/public_html/libraries/joomla/registry/format/ini.php on line 281

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JPluginHelper::importPlugin() should not be called statically in /home/zephyr/public_html/index.php on line 41

Strict Standards: Non-static method JPluginHelper::_load() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 92

Strict Standards: Non-static method JPluginHelper::_import() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 97

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Redefining already defined constructor for class JPlugin in /home/zephyr/public_html/libraries/joomla/plugin/plugin.php on line 75

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Declaration of JEvent::update() should be compatible with JObserver::update() in /home/zephyr/public_html/libraries/joomla/event/event.php on line 29

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JDispatcher::getInstance() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 140

Strict Standards: Non-static method JPluginHelper::getPlugin() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 147

Strict Standards: Non-static method JPluginHelper::_load() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 41

Strict Standards: Non-static method JPluginHelper::_import() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 97

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JDispatcher::getInstance() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 140

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JPluginHelper::_import() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 97

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JDispatcher::getInstance() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 140

Strict Standards: Non-static method JPluginHelper::getPlugin() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 147

Strict Standards: Non-static method JPluginHelper::_load() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 41

Strict Standards: Non-static method JPluginHelper::_import() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 97

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JDispatcher::getInstance() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 140

Strict Standards: Non-static method JPluginHelper::getPlugin() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 147

Strict Standards: Non-static method JPluginHelper::_load() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 41

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

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Strict Standards: Non-static method JPluginHelper::_import() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 97

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JDispatcher::getInstance() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 140

Strict Standards: Non-static method JPluginHelper::getPlugin() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 147

Strict Standards: Non-static method JPluginHelper::_load() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 41

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Declaration of database::loadObject() should be compatible with JDatabaseMySQL::loadObject() in /home/zephyr/public_html/plugins/system/legacy/mysql.php on line 80

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/plugins/system/legacy/mysql.php on line 19

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

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Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/plugins/system/legacy/mambothandler.php on line 19

Strict Standards: Non-static method JPluginHelper::_import() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 97

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Strict Standards: Non-static method JDispatcher::getInstance() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 140

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

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Strict Standards: Non-static method JPluginHelper::_import() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 97

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Strict Standards: Non-static method JDispatcher::getInstance() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 140

Strict Standards: Non-static method JPluginHelper::getPlugin() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 147

Strict Standards: Non-static method JPluginHelper::_load() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 41

Strict Standards: Non-static method JPluginHelper::_import() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 97

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

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Strict Standards: Non-static method JDispatcher::getInstance() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 140

Strict Standards: Non-static method JPluginHelper::getPlugin() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 147

Strict Standards: Non-static method JPluginHelper::_load() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 41

Strict Standards: Non-static method JPluginHelper::_import() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 97

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Strict Standards: Non-static method JPluginHelper::_load() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 41

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Strict Standards: Redefining already defined constructor for class sh_Net_URL in /home/zephyr/public_html/administrator/components/com_sh404sef/sh404sef.class.php on line 2412

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Strict Standards: Non-static method JRequest::_cleanVar() should not be called statically in /home/zephyr/public_html/libraries/joomla/environment/request.php on line 151

Strict Standards: Non-static method JFilterInput::getInstance() should not be called statically in /home/zephyr/public_html/libraries/joomla/environment/request.php on line 577

Strict Standards: Non-static method JApplicationHelper::getClientInfo() should not be called statically in /home/zephyr/public_html/administrator/components/com_sh404sef/sh404sef.class.php on line 2175

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLanguage::getLanguagePath() should not be called statically in /home/zephyr/public_html/administrator/components/com_sh404sef/sh404sef.class.php on line 2179

Strict Standards: Non-static method JFolder::folders() should not be called statically in /home/zephyr/public_html/administrator/components/com_sh404sef/sh404sef.class.php on line 2180

Strict Standards: Non-static method JPath::clean() should not be called statically in /home/zephyr/public_html/libraries/joomla/filesystem/folder.php on line 475

Strict Standards: Non-static method JFolder::files() should not be called statically in /home/zephyr/public_html/administrator/components/com_sh404sef/sh404sef.class.php on line 2184

Strict Standards: Non-static method JPath::clean() should not be called statically in /home/zephyr/public_html/libraries/joomla/filesystem/folder.php on line 414

Strict Standards: Non-static method JFactory::getXMLParser() should not be called statically in /home/zephyr/public_html/administrator/components/com_sh404sef/sh404sef.class.php on line 2186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

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Strict Standards: Non-static method JPath::clean() should not be called statically in /home/zephyr/public_html/libraries/joomla/filesystem/folder.php on line 414

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Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

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Strict Standards: Non-static method JPath::clean() should not be called statically in /home/zephyr/public_html/libraries/joomla/filesystem/folder.php on line 414

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Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

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Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/joomla/cache/cache.php on line 19

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Declaration of JCacheStorage::get() should be compatible with JObject::get($property, $default = NULL) in /home/zephyr/public_html/libraries/joomla/cache/storage.php on line 173

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JRequest::getInt() should not be called statically in /home/zephyr/public_html/index.php on line 55

Strict Standards: Non-static method JRequest::getVar() should not be called statically in /home/zephyr/public_html/libraries/joomla/environment/request.php on line 179

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

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Strict Standards: Non-static method JRequest::getCmd() should not be called statically in /home/zephyr/public_html/plugins/system/plg_reg_redirector.php on line 16

Strict Standards: Non-static method JRequest::getVar() should not be called statically in /home/zephyr/public_html/libraries/joomla/environment/request.php on line 255

Strict Standards: Non-static method JRequest::_cleanVar() should not be called statically in /home/zephyr/public_html/libraries/joomla/environment/request.php on line 140

Strict Standards: Non-static method JFilterInput::getInstance() should not be called statically in /home/zephyr/public_html/libraries/joomla/environment/request.php on line 577

Strict Standards: Non-static method JRequest::getCmd() should not be called statically in /home/zephyr/public_html/plugins/system/plg_reg_redirector.php on line 17

Strict Standards: Non-static method JRequest::getVar() should not be called statically in /home/zephyr/public_html/libraries/joomla/environment/request.php on line 255

Strict Standards: Non-static method JRequest::_cleanVar() should not be called statically in /home/zephyr/public_html/libraries/joomla/environment/request.php on line 151

Strict Standards: Non-static method JFilterInput::getInstance() should not be called statically in /home/zephyr/public_html/libraries/joomla/environment/request.php on line 577

Strict Standards: Non-static method JRequest::getCmd() should not be called statically in /home/zephyr/public_html/plugins/system/plg_reg_redirector.php on line 18

Strict Standards: Non-static method JRequest::getVar() should not be called statically in /home/zephyr/public_html/libraries/joomla/environment/request.php on line 255

Strict Standards: Non-static method JRequest::_cleanVar() should not be called statically in /home/zephyr/public_html/libraries/joomla/environment/request.php on line 140

Strict Standards: Non-static method JFilterInput::getInstance() should not be called statically in /home/zephyr/public_html/libraries/joomla/environment/request.php on line 577

Strict Standards: Non-static method JPluginHelper::getPlugin() should not be called statically in /home/zephyr/public_html/plugins/system/plg_reg_redirector.php on line 21

Strict Standards: Non-static method JPluginHelper::_load() should not be called statically in /home/zephyr/public_html/libraries/joomla/plugin/helper.php on line 41

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JRequest::getCmd() should not be called statically in /home/zephyr/public_html/index.php on line 67

Strict Standards: Non-static method JRequest::getVar() should not be called statically in /home/zephyr/public_html/libraries/joomla/environment/request.php on line 255

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

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Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/joomla/document/document.php on line 19

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

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Strict Standards: Declaration of JDocumentHTML::setBuffer() should be compatible with JDocument::setBuffer($content) in /home/zephyr/public_html/libraries/joomla/document/html/html.php on line 394

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

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Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

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Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

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Strict Standards: Non-static method JResponse::toString() should not be called statically in /home/zephyr/public_html/index.php on line 88

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Strict Standards: Non-static method JResponse::allowCache() should not be called statically in /home/zephyr/public_html/libraries/joomla/environment/response.php on line 197

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2/26/10 Science Daily: "Innate Mechanisms Can Control Disease Progression in HIV-Positive Patients", Barcelona, Spain research findings on dendritic cell
Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

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Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Declaration of ContentController::display() should be compatible with JController::display($cachable = false) in /home/zephyr/public_html/components/com_content/controller.php on line 28

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: call_user_func_array() expects parameter 1 to be a valid callback, non-static method JHTMLBehavior::caption() should not be called statically in /home/zephyr/public_html/libraries/joomla/html/html.php on line 91

Strict Standards: Non-static method JHTML::script() should not be called statically in /home/zephyr/public_html/libraries/joomla/html/html/behavior.php on line 63

Strict Standards: Non-static method JHTML::_() should not be called statically in /home/zephyr/public_html/libraries/joomla/html/html.php on line 172

Strict Standards: call_user_func_array() expects parameter 1 to be a valid callback, non-static method JHTMLBehavior::mootools() should not be called statically in /home/zephyr/public_html/libraries/joomla/html/html.php on line 91

Strict Standards: Non-static method JFactory::getConfig() should not be called statically in /home/zephyr/public_html/libraries/joomla/html/html/behavior.php on line 46

Strict Standards: Non-static method JHTML::script() should not be called statically in /home/zephyr/public_html/libraries/joomla/html/html/behavior.php on line 56

Strict Standards: Non-static method JURI::root() should not be called statically in /home/zephyr/public_html/libraries/joomla/html/html.php on line 176

Strict Standards: Non-static method JFactory::getDocument() should not be called statically in /home/zephyr/public_html/libraries/joomla/html/html.php on line 179

Strict Standards: Non-static method JURI::root() should not be called statically in /home/zephyr/public_html/libraries/joomla/html/html.php on line 176

Strict Standards: Non-static method JFactory::getDocument() should not be called statically in /home/zephyr/public_html/libraries/joomla/html/html.php on line 179

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Declaration of JCacheView::get() should be compatible with JCache::get($id, $group = NULL) in /home/zephyr/public_html/libraries/joomla/cache/handler/view.php on line 150

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 71

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: Non-static method JLoader::load() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 161

Strict Standards: Non-static method JLoader::register() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 138

Strict Standards: call_user_func_array() expects parameter 1 to be a valid callback, non-static method JHTMLBehavior::tooltip() should not be called statically in /home/zephyr/public_html/libraries/joomla/html/html.php on line 91

Strict Standards: Non-static method JHTMLBehavior::mootools() should not be called statically in /home/zephyr/public_html/libraries/joomla/html/html/behavior.php on line 87

Strict Standards: Non-static method JHTMLBehavior::_getJSObject() should not be called statically in /home/zephyr/public_html/libraries/joomla/html/html/behavior.php on line 105

Strict Standards: Non-static method JFactory::getDocument() should not be called statically in /home/zephyr/public_html/libraries/joomla/html/html/behavior.php on line 108

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: call_user_func_array() expects parameter 1 to be a valid callback, non-static method JHTMLBehavior::tooltip() should not be called statically in /home/zephyr/public_html/libraries/joomla/html/html.php on line 91

Strict Standards: Non-static method JHTMLBehavior::mootools() should not be called statically in /home/zephyr/public_html/libraries/joomla/html/html/behavior.php on line 87

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

Strict Standards: Non-static method JLoader::import() should not be called statically in /home/zephyr/public_html/libraries/loader.php on line 186

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2/26/10 Science Daily: "Innate Mechanisms Can Control Disease Progression in HIV-Positive Patients", Barcelona, Spain research findings on dendritic cell
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E-mail
  

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Monday, 12 April 2010 17:13

Innate Immune Mechanisms Can Control Disease Progression in HIV-Positive Patients

ScienceDaily (Feb. 26, 2010) — HIV/AIDS remains one of the world's most significant public health challenges, particularly in developing countries. The Human Immunodeficiency Virus (HIV-1), the variant responsible for the pandemic, has the ability to infect different cell types such as T cells, macrophages and dendritic cells (DC). These latter cells are crucial in the defense against infectious agents and play a major role in viral pathogenesis.
 
A new study, led by researchers from Hospital Clinic de Barcelona-IDIBAPS, within the framework of HIVACAT, shows for the first time that dendritic cells in HIV-infected patients who spontaneously control the infection produce high levels of α-defensins 1-3. This is associated with slower disease progression, suggesting potential diagnostic, therapeutic and preventive implications.
The first author of this study is Dr. Marta Rodriguez-Garcia, Emili Letang Fellowship award from Hospital Clinic of Barcelona for her work in this line of research, and currently a postdoc at The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard. The senior researchers of the study are Dr. Teresa Gallart, from the Immunology Service of Hospital Clinic and collaborator of the IDIBAPS team on Infectious Diseases and AIDS, and Dr. Josep M ª Gatell, Head of the Infectious Diseases Department at the Hospital Clinic and leader of the same IDIBAPS team.
The study was done in collaboration with the Catalan Center for HIV Vaccine Research and Development (HIVACAT), a public-private partnership involving IrsiCaixa Foundation and the Infectious Diseases Department at the Hospital Clinic of Barcelona. The research conducted within this initiative is made in coordination with Esteve and with the support of "La Caixa" Foundation and the Health and the Innovation, Universities and Enterprise Departments of the Generalitat de Catalunya.
Defensins are endogenous antimicrobial peptides with broad-spectrum antimicrobial properties and immunomodulatory effects. They have a potent anti-HIV activity, acting directly on the virus and also in target cells. According to its structure, human defensins are classified into two subfamilies: α-defensins and β-defensins, both with anti-HIV activity. The α-defensins, also known as human neutrophil peptides, are stored in neutrophils and, to a lesser extent, in other types of leukocytes. Although the anti-HIV activity of α-defensins1-3 has been clearly demonstrated in vitro, their possible protective role during HIV infection in vivo remains uncertain.
The authors recently demonstrated that α-defensins1-3 are produced by monocyte-derived immature dendritic cells (MDDC) in healthy individuals and they are able to modulate the maduration and differentiation process of MDDC. Dendritic cells (DC) are the main antigen-presenting cells and play a key role in the innate immune response against different viral infections, especially during the response generated against HIV. Due to their mucosal localization, DC are thought to be one of the first cells that encounter the HIV and, after migration to the lymph nodes, they would mediate the transmission of HIV-1 virions to CD4 T cells, the main source of HIV-1 replication and dissemination. For this study, a valid model of in vivo myeloid DC, the MDDC, was analysed. These might be one of the key cells involved in early HIV infection, and therefore their capacity to produce and release α-defensins1-3 by DC may have physiological relevance.
The study enrolled healthy, non-infected controls and HIV-1-infected subjects. These HIV-1-infected individuals were classified as: elite controllers (patients able to spontaneously control VIH infection in the absence of therapy, with plasma viral loads below 50 RNA copies/ml and that constitute the 5% of the infected population), viremic controllers (with PVLs higher than 50 and lower than 5000 RNA copies/ml without therapy), viremic non-controllers (with PVLs higher than 5000 RNA copies/ml without therapy) and patients with antiretroviral therapy (HAART). All patients had CD4 T cell counts higher than 450 cell/mm3. Results revealed that immature dendritic cells from HIV-infected patients who control the infection produced higher levels of α-defensins1-3 than the non-infected control group and these levels were associated with a better control of HIV infection and slower disease progression. The study of controller patients, especially elite controllers, is of particular relevance since these individuals demonstrate that natural control of HIV replication in the absence of antiretroviral therapy is possible.
The findings of this study show that of α-defensins1-3 may be potential prophylactic agents and open a new line of investigation to treat HIV / AIDS, although further studies will be needed to determine the possible value of these molecules as an important diagnostic and therapeutic tool to arrest or slow the replication of HIV in infected patients.
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Monday, 12 April 2010 18:12 )
 
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CROI 2011


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  • Wednesday 9th March 2011
    This is our final bulletin from CROI 2011. We hope you have found our news coverage useful. You can find all our coverage at www.aidsmap.com/croi2011, including the news reports and bulletins.We are always looking for ways of improving and developing our resources – so if you have any comments that you would like
  • Thursday 3rd March 2011
    There is increasing evidence of the transmission of HIV strains with resistance to anti-HIV drugs in low- and middle-income countries. Research in eleven sub-Saharan African countries showed that the chances of detecting transmitted resistance increased by over a third each year that a country had been scaling up HIV treatment. A separate study involving people recently diagnosed
  • Wednesday 2nd March 2011
    A new type of anti-HIV drug that targets the first step in HIV’s entry into cells has done well in a Phase IIa study. Currently known as BMS-663068, the drug was shown to be safe and to work against the virus. HIV cell entry is a three-step process. The virus must first attach to the

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Studies


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Controllers in Study

 Donation Thermometer
 Donation Thermometer
 Donation Thermometer
86%

Our Goal:
2000
Currently:
1725
Updated:
December 30, 2009

Current Breakdown: 505 Elite Controllers 1009 Viremic Controllers 211 Other


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